LongITools

Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

OBJECTIVES

  • Develop machine learning tools based on full resolution exposome data for cardio-metabolic risk prediction
  • Establish an open-source toolbox for analysing longitudinal biomedical data including multi-source and multi-type exposome data
  • Implement defined user and clinical requirements and pilot test a mobile application for cardio-metabolic monitoring

ROLES

  • Develop a catalogue of longitudinal multi-dimensional datasets under a FAIR (findable, accessible, interoperable and re-usable) data infrastructure
  • Develop, implement and advance epidemiological, statistical and computational methodologies to incorporate the longitudinal dimensions in exposome-wide associations and cross-omic studies of health and disease
  • Explore and unravel, using data-driven methods, the association between environmental exposures and the risk of cardio-metabolic disease across the life-course
  • Implement, pilot and demonstrate new healthcare applications for personal risk assessment and public health and policy planning
  • Perform economic and econometric assessments to identify the health and cost benefits of time-dependent investments in addressing the impact of environmental exposures across the life course

PARTNERS   

NO. INSTITUTION COUNTRY
1
Imperial College London
United Kingdom
2
Erasmus MC
Nederland
3
Beta Technology
United Kingdom
4
University of Eastern Finland
Finland
5
Chalmers University of Technology
Sweden
6
University Medical Center Groningen
Nederland
7
National Institute of Medical Research
France
8
University College London
United Kingdom
9
University of Utrecht
Nederland
10
University of Surrey
United Kingdom
11
Amsterdam Medical Center
Nederland
12
University of Oslo
Norway
13
University of Bristol
United Kingdom
14
Universitat Pompeu Fabra
Spain
15
AB-Acus
Italy
16
Cynexo
Italy
17
University of Rome
Italy
earlycause-logo
earlycause-logo

Funding institution

European Commision

Project number

874739

Project budget

11 997 448,75 €

UB's budget

716 250,00 €

Project Coordinator

Sylvain Sebert (University of Oulu)

UB's Principal Investigator

Karim Lekadir

BCN-AIM's role

Leader WP7

Official website

longitools.org

Twitter

twitter.com/LongITools

Mail

karim.lekadir@ub.edu